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Norvasc and chest pain: "Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Side effects of Amlodipine. The heart to pump and reducing its workload. Norvasc blocks the transport of calcium into the smooth muscle cells lining the coronary arteries and other arteries of the body. Amlodipine is in a class of medications called calcium channel blockers. While you are taking Amlodipine, do not start or stop taking your other medicines including any other blood pressure medicines, without talking to your doctor if you experience headache, insomnia, nausea, diarrhea, or constipation. Amlodipine controls high blood pressure or angina. Side effects of Norvasc are headache and edema of the lower extremities. Amlodipine is in a class of medications called calcium channel blockers."